While we cannot completely discount a role for GLP-1R-mediated changes in blood pressure that could influence water intake, it is important to note that these blood pressure changes are more transient than the longer-lasting hypodipsic effects following GLP-1R activation, making it unlikely that the intake suppression was exclusively related to changes in blood pressure
When evaluating GLP-1s, its important to weigh potential riskslike muscle loss, metabolic slowdown, and post-treatment insulin resistance
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PMID: 41866450 J Ethnopharmacol The modified Zuojin formula (SQQT) associates ILC2-linked JAK-2/STAT5/c-Myc cascade and gastric metaplasia regression
[DOI] [PMC free article] [PubMed] [Google Scholar] 89.Vaisse C, Halaas JL, Horvath CM, Darnell JE, Stoffel M, Friedman JM