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thyroid, kidney, or liver dysfunction, skin rash, and complications with intravenous catheters such as infection and inflammation of the vein

Although this is not considered clinically relevant in most cases, caution should be exercised when co-administering medications with narrow therapeutic windows (such as levothyroxine and warfarin) (713)

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1 Poor prognostic signs include multi-organ failure, which may involve cerebral edema, renal failure, profound hypoglycemia and lactic acidosis, any signs of which should prompt an immediate liver transplant evaluation