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and (iii) promoting the proliferation of dermal papilla cells and inhibiting their apoptosis to stimulate the growth of hair follicles and hairs [5,27,28]

In certain contexts, this interaction appears to suppress the apoptotic removal of senescent cells

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Chemical structures of vitamin E isoforms The figure shows the chemical structures of vitamin E isoforms in two panels: Panel A: Natural -tocopherol, produced by plants, has an RRR -configuration at the 2, 4, and 8 of the molecule

Addressing the unique challenges posed by chronic wounds in the aged population will require interdisciplinary collaboration to advance our understanding of skin aging and wound healing mechanisms