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Description

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Hickman S, Izzy S, Sen P, Morsett L, El Khoury J

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Multiple studies have indicated that GLP-1s may improve a wide range of mental health outcomes, such as depressive symptoms and alcohol and substance use disorders

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On the other hand, treatment of cancer cells with the anti-IGF-IR mAb cixutumumab paradoxically triggers cancer cells to produce IGF2, which in turn recruits macrophages and fibroblasts to promote angiogenesis and metastasis thereby hampering the efficacy of cixutumumab [190]

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in recent years

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