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The SURMOUNT clinical trial program provides robust evidence for Zepbound's sustained effectiveness over extended treatment periods

Bibcode:2021NatSR..1121179O

Lilly PACKAGE LABEL - Mounjaro Prefilled Pen (Autoinjector) - 7.5 mg/0.5 mL Dose NDC 0002-1484-80 Mounjaro (tirzepatide) injection 7.5 mg/0.5 mL Use one pen every week

Reported incidences in those receiving a 12mg/weekly dose of retatrutide were [21]: Nausea (45% of participants) Vomiting (19%) Constipation (16%) Diarrhea (15%) Cardiac arrhythmia (11%) Fatigue (10%) Increased pancreatic enzyme (lipase) levels (8%) Injection site reactions (8%) Liver issues in 2 participants (3%) Pancreatitis in 1 participant (2%) Both tirzepatide and retatrutide share similar contraindications, including advice against their use during pregnancy and breastfeeding

Compounded preparations have not been separately studied, and individual results vary