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instead, F is determined by comparing area under the curve of a plasma concentration versus time plot for an orally-administered dose with the area under the curve following an IV dose of the same amount of the same drug to the same patient

Therefore, we questioned whether data from animal studies is sufficient to extrapolate to human populations for the purposes of demonstrating substantial clinical improvement

This is why the plotter is arguably more valuable for retatrutide users than for any other GLP-1 medication

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