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Stacking combining multiple peptides to create powerful synergy

Here we showed that ScGrx7 has two different glutathione interaction sites, a glutathione-scaffold site, which includes Glu170 and interacts with GSSR, and a glutathione activator site, which includes Lys105 and interacts with GSH

Leaving the vial at room temperature for even a few hours accelerates degradation

A major limitation is that current evidence for direct molecular crosstalk between ferroptosis and cuproptosis derives from studies in different cancer types or cell line models

The number of articles and potential biomarkers studied, classified by category and country, are presented in Table 1