It produces a weight loss, on average, of about 3 kg (de Silva VA et al, BMC Psychiatry 2016;16(1):341) or about a 3% reduction in body weight, compared to a 1% reduction with placebo (Jarskog LF et al, Am J Psychiatry 2013;170(9):10321040)
It helps you feel full longer, reduces cravings, and slows digestion making it easier to eat less without feeling deprived
Prakash, Krishna et al (2022) Trncated Human IRF-1 (1-233) protein shows neutral transcriptional effect on expression of Bax, survivin, Bcl2 and cyclin D1 genes in HEK293T cell line
Galloway, D.C., Blacke, D.G., Shepherd, A.G
Important Context : These are hypothesis-generating findings requiring prospective, controlled trials before expanding clinical indications