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American Association of Poison Control Centers

Piperlongumine rapidly induces the death of human pancreatic cancer cells mainly through the induction of ferroptosis

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methylenetetrahydrofolate dehydrogenase (MTHFD) and aldehyde dehydrogenases (ALDHs) in folate metabolism (Fig

For example, the most commonly used treatment is N-acetylcysteine (NAC), which helps replenish glutathione in the liver, allowing it to neutralize toxic metabolites