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British Journal of Pharmacology, 176(S1), S397S493

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The mechanisms underlying these CV benefits include promoting myocardial glucose uptake and utilization, reducing oxidative stress, inhibiting cardiomyocyte apoptosis, vasodilation, improving coronary blood flow, natriuresis, anti-inflammatory effects, renal protection, reducing plaque formation, and neurohormonal regulation (22)

Clinicians should watch for it in the first few months after starting a patient on a GLP-1.For people prone to alcohol- or triglyceride-induced pancreatitis, GLP-1 drugs may actually reduce those risks.Bottom line: the answer to "do GLP-1s cause pancreatitis?" depends on the cause of pancreatitis.Paper led by Yan Xie @Biostayan and Taeyoung Choi

Table 4 The context-dependent and species-specific functions of the PPAR (gamma) regulatory axis in the corpus luteum activity