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To assess the associations of semaglutide with recurrent CUD, the study population included 8196 patients with T2D who had active medical encounters for T2D diagnosis in 12/20175/2021, were for the first time prescribed semaglutide or non-GLP1-1RA anti-diabetes medications during 12/20175/2021(index event), had a diagnosis of CUD on or before the index event, and had a diagnosis of at least one of obesity-associated comorbidities on or before the index event

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A 2022 study in Nature Medicine found a mean body weight reduction of 15.2% over 104 weeks, compared to 2.6% for the placebo group

Hjorth, E

If you consistently underdose by 10%, your weight loss will plateau earlier than expected