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10.1016/j.jconrel.2011.05.024 12 BourgeauxV.AufradetE.CampionY.De SouzaG.HorandF.BessaadA.et al (2012)

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In vitro and animal-model studies have examined its association with cytoskeletal organization, nitric-oxide-related signaling, angiogenesis-related mechanisms, and cellular adaptation under physiological stress

These properties are exemplified in a study by Demkovych et al

Similar to the reversible ADP-ribosylation of proteins and DNA, the ADP-ribosylation of RNA can also be efficiently reversed by several cellular hydrolases including TARG1, MACROD1-2, PARG, NUDT16 and ARH3 viruses