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Many growth hormone therapies can lead to imbalances in other hormone systems, such as cortisol or prolactin, which can cause unwanted side effects like increased stress or weight gain

doi: 10.1007/s11684-019-0729-1

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Immune imbalance inhibits mitochondrial oxidative phosphorylation and activates glycolysis through pro-inflammatory factors such as IL-1 and IL-6, as well as NLRP3 inflammasome signaling molecules, resulting in metabolic remodeling

Further well-designed, multicenter randomized controlled trials employing standardized and sensitive apnea detection methods are essential to definitively evaluate this potential application (45, 78)