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Perera E, et al

Injectable GHK-Cu requires medical oversight

Published research has examined DSIP in animal models of slow-wave sleep, circadian rhythm, stress-axis signalling, analgesia, thermoregulation and oxidative stress

First, it disrupts the process of melanin synthesis by inducing the release of high mobility group box 1 (HMGB1) protein, thus downregulating the melanin biosynthesis-related proteins: melanocyte-inducing transcription factor, tyrosinase, tyrosinase-related protein-1, tyrosinase-related protein-2, RAB27A and fascin actin-bundling protein 1 [17, 18]

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