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Therefore, the combination of SGLT2 inhibitors and GLP-1 receptor agonists provides an effective approach for modifying the development of a medical condition and enhancing patient outcomes in high-risk groups [60,61]

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Such observation could be attributed to the anti-apoptotic effect of GIP on osteoblasts (71), as osteoblast-derived hormones such as osteocalcin and lipocalcin 2 are implicated in regulating peripheral metabolism and modulate food intake (72)

Yong, T