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Although our primary endpoints of SARS-CoV-2 infection rates in Cohort 1 and disease progression in Cohort 2 were unmet, our analysis of the secondary endpoints suggests that LCLT supplementation modulates coagulation via increased platelet count and decreased fibrinogen levels

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Clinical outcomes such as cirrhosis progression, liver transplant, and all-cause mortality are recognized as solid endpoints for evaluating drug efficacy in MASLD