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In a clinical trial on 6 men, drinking coffee (165-400 mL/day) increased gallbladder contractions and the levels of the hormone that stimulates bile release (cholecystokinin) [2, 21]

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Alberto Caballero-Garca, David C Noriega-Gonzlez, Enrique Roche, Franchek Drobnic, Alfredo Crdova, 2023 May 31 - Cardiac Metabolism in Heart Failure - Implications beyond ATP production