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Helicobacter pylori infection and antioxidants can modulate the genotoxic effects of heterocyclic amines in gastric mucosa cells

The study protocol was registered in the International Prospective Register of systematic reviews PROSPERO (CRD420251002447)

Long-term use appears well-tolerated when dosing is appropriate and monitored

Patients receive counseling on hydration, electrolytes, and protein intake, which are critical to maintaining muscle while taking appetite-suppressing medication

To reveal the role of targeting ligands in the cellular uptake processes, alanine and GSH ligands were added at high concentration (5 mM each) in co-treatment with the targeted nanocarriers