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Individual results vary, and DSIP is not appropriate for everyone: People with chronic insomnia that has not responded adequately to behavioral or conventional pharmacological interventions Shift workers or frequent travelers are dealing with circadian rhythm disruption Individuals experiencing stress-related sleep disturbances and elevated cortisol patterns Athletes and active individuals seeking to optimize recovery through improved sleep quality Older adults experiencing age-related changes in sleep architecture and hormone secretion People who have experienced side effects from traditional sleep medications and are seeking non-sedating alternatives Individuals managing chronic pain conditions that interfere with restorative sleep Struggling with sleep and recovery

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For example, one early protocol for substance use disorders employed 500-1,000 mg of NAD+ per day delivered by slow intravenous infusion over several consecutive days

Chronic sleep deprivation can lead to higher oxidative stress, which uses up your antioxidant reserves