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They are common in skin care routines

China has also begun to pay attention to the risk of thyroid cancer induced by GLP-1RA, and this warning has been added to the drug instructions of some GLP-1RAs

Modern medicinal chemistry can extend peptide half-life, improve receptor selectivity, reduce degradation and change how a peptide is delivered

Interestingly, the question of splitting tirzepatide doses comes up just as frequently, and the pharmacokinetic rationale is similar

If erectile function and testosterone levels improve but GLP-1 RA therapy remains clinically necessary, re-initiation at a previously tolerated lower dose or switching to a different GLP-1 RA may be considered, with close monitoring and informed consent