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Participants transitioning from Zepbound to Foundayo started at an average body weight of 115.8 kg (255.3 lbs), decreased to 90.9 kg (200.4 lbs) at the initiation of oral maintenance, and averaged 95.9 kg (211.4 lbs) after 52 weeks

Cardiovascular and renal outcomes of glucagon-like peptide 1 receptor agonists among patients with and without type 2 diabetes mellitus: a meta-analysis of randomized placebo-controlled trials

The complex biotechnological manufacturing of peptide-based therapies, which requires sophisticated facilities and lengthy production timelines, makes rapid scaling a logistical challenge

The request applying to Novo Nordisk's Wegovy (semaglutide) and Saxenda (liraglutide), as well as Eli Lilly's Zepbound (tirzepatide) follows a new review of the drugs' safety, which the agency said did not identify any increased risk

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