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Notably, PG-102 showed the lowest CD45 area among groups, suggesting a possible trend toward reduced local inflammation compared to semaglutide or tirzepatide (Supplementary Fig
On the other hand, any effect to the cerebellar posterior lobe, notably lobule VI, lobule VII (including crus I and II of lobule VIIA, and lobule VIIB), and lobule IX leads to CCAS [11], as these lobes are interconnected to different cerebral areas [208]
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A dual staining was performed with CD4: FITC (CC8, IgG2a) and CD8a: RPE (CC63, IgG2a) and another with CD21: PE (CC51, IgG2b) and CD14: FITC (CC-G33, IgG1)