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As whole-transcriptome analysis tools have grown more accessible, researchers have begun to characterize just how broad GHK-Cu's influence on gene expression actually is making this short copper-binding tripeptide a focal point of regenerative and dermatological research

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The lower RMSF values for residues 200 to 400 in the Arbutin_d mode are hypothesized to be due to the hydroxyphenyl group of Arbutin_d facing the L3 region, where R289 tends to interact with the hydroxyphenyl group of Arbutin, stabilizing this region

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