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Such disorders are characterized by malfunctions in the nervous system and may occur in otherwise healthy patients after going through an infectious disease [366]
The multifaceted mechanism of action of 5FU involves direct incorporation of its metabolites into DNA (FdUTP) and RNA (FUTP), as well as inhibition of thymidylate synthase (TS) via FdUMP 4,5 , making it more difficult to identify rational combination partners that would enhance clinical responses without eliciting adverse systemic toxicity
M., & Cho, M
It promoted hair regrowth by effectively inducing the anagen phase in telogenic C57BL/6 mice
GI symptoms like nausea or bloating are most pronounced in the first 72 hours after the initial injection and diminish progressively with each subsequent dose as homocysteine clearance pathways upregulate
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