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Research Background The oral tablet format of GHK-Cu enables research into oral bioavailability and systemic distribution of copper peptides
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Antibodies used: p53 (32532 (D2H9O), 1:1000 Cell Signalling, Danvers, MA, United States), human p53 (sc-126 (DO-1), 1:3000, Santa Cruz Biotechnology, Dallas, Texas, United States), GAPDH (2118 (14C10), 1:5000, Cell Signalling, Danvers, MA, United States), -actin (Ab6276 (AC-15), 1:250,000, Abcam, Cambridge, United Kingdom), vinculin (PA5-29688, 1:1000, Thermo Fisher Scientific, Waltham, MA, United States), MMP12 (ab52897 (EP1261Y), 1:1000, Abcam, Cambridge, United Kingdom)
In univariable analyses, sex, reporting country, and drug category were significantly associated with the occurrence of ICI-related adverse events