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From these findings and the fact that glutathione is essential for lymphocyte proliferation and immune responses, , we hypothesized that abundant cystine/cysteine in the kidneys forms a unique metabolic microenvironment that supports ectopic lymphocyte proliferation, leading to the formation of TLS

Both omega-3 and omega-6 PUFAs play significant roles in cardiovascular, inflammatory, metabolic, neurological, and psychiatric health (14, 49, 50)

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Consequently, obese individuals have attenuated GH responses to GH secretagogues (68)