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Under homeostatic conditions, 15-HpETE-PE is rapidly and specifically metabolized by the GSH-dependent GPX4 to the nonreactive hydroxy derivative 15-HETE-PE (6, 14)

The study period was also the data analysis period, given that our research was a cross-sectional study

Epithalon is typically administered via subcutaneous injection

Activating pathways for creation of NADPH has been shown to protect RPE cells from oxidative damage 74 , and our findings indicate that for developing mouse retinas with RP in which all rods have been lost a possible intervention strategy would be to stimulate synthesis of NADPH

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