Pay in 4 interest-free payments of $6.66 Learn more
Ships within 48 hours · Estimated delivery Aug 4 - Aug 9
SS-31 addresses the cellular mechanism underlying this pattern Longevity & Healthy Aging Mitochondrial decline is considered one of the nine hallmarks of cellular aging identified in the landmark 2013 paper by Lopez-Otin et al
M., Parris, E
2017;8 doi: 10.3389/fphar.2017.00608
( 2 O 2 in the bloodstream trypomastigotes compared to the epimastigote stage (Gonalves et al., 2 and H 2 O 2 formation (Gonalves et al., 2009), they may still be exposed to excessive oxidative stress due to mitochondrial remodeling and increased ROS production (Gonalves et al., Drugs-Derived Oxidative Stress Treatment with anti-parasite drugs, benznidazole (BZ) and nifurtimox (NFX), also exposes the parasite to oxidative stress
p53 can directly bind to the promoter region of SLC7A11 in relevant cells, suppressing its transcriptional activity, thereby inhibiting cystine uptake, reducing GSH synthesis, and inducing ferroptosis (54, 55)
US$ 29.31
US$ 23.21
US$ 25.32
US$ 29.25
