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Schizophrenia could also be a context for implementing these immunometabolic strategies ( Previous clinical observations indicate that a rapid and substantial reduction in body mass may result in significant mental disturbances

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Taken together, glutamatergic abnormalities are a consistent feature of mid-life depression, with lower mGluR5 across cortical and hippocampal regions linked to symptom severity and cognitive deficits, and ketamine-induced glutamatergic modulation associated with clinical improvement

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