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Plants and most animals can produce their own vitamin C from glucuronic acid using a special enzyme

13) Addictions Various drugs of abuse (such as cocaine and methamphetamines), as well as alcohol, increase the production of reactive oxygen species

222-224 Stress and anxiety appear to contribute to gut hypersensitivity via modulation of neural pain-processing pathways by glucocorticoid hormones, which are also called stress hormones. 225 Moreover, alterations of the microbiome have been observed in mood disorders, which frequently also present with IBS symptoms

Although the weight loss observed in this study was less pronounced than in populations without psychiatric comorbidities, this could be due to shorter trial durations and concurrent use of medications known to promote weight gain, such as clozapine or olanzapine, and the influence of antidepressants

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