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Also, overexpression of heme oxygenase-1, a stress-induced enzyme that produces endogenous carbon monoxide, has been found to protect dopaminergic neurons from neurotoxicity in an animal model of Parkinsons. In addition, nicotine, a major constituent of cigarette smoke, has been found to be ineffective at slowing the diseases progression in a recently reported clinical trial

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People who work in these industries and repeatedly inhale asbestos particles are the most at risk for developing asbestosis

2, Associated Press, May 15, 2001, retrieved from LexisNexis database

Therefore, personality factors play an important determining role in SUD (Ismail et al., 2021)