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At the DNA level, the nicotine-free extract caused more frequent DNA breaks, but they observed that the nicotine extract caused three times the amount of breakdown per individual DNA strand

1 2 3 4 5 6 7 8 9 "Social reformers and regulation: the prohibition of cigarettes in the United States and Canada" (PDF)

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When, at the climax, she impulsively steps forward, her hands extended, her beautiful face full of feeling, something at the core of her way of making music drama is still alive