Analysis of the transcriptomic changes (based on RNA sequencing) in 3D human airway cells due to exposure to experimentally-generated aerosols from the THP1.0 and THS2.2 heated tobacco products suggested that the THP1.0 heated tobacco product had a markedly lower transcriptomic effect compared to the THS2.2 heated tobacco product (Haswell et al., 2018)
Lipari RN, Williams MR, Copello EAP, Pemberton MR
Cardiff to me is one of the milder blends in the Esoterica line, but flavorful enough that I like to keep some around for a break from the heavier blends
Discuss areas of ongoing concern: disparities in tobacco use, youth appeal of e-cigarettes and nicotine pouches
cigars and pipes were also tools of the tobacco trade, though during WWI, cigarettes overtook pipe smoking as the most popular way to inhale nicotine because smoking a pipe could get you killed (well, killed faster, anyway)