Semaglutide carries an FDA boxed warning based on thyroid C-cell tumors observed in high-dose animal studies, but no human cases of thyroid cancer have been confirmed in clinical trials or real-world use
However, whether glucoraphanin intake in healthy adults improves and maintains liver function is not fully understood as these previous studies have several limitations, including focusing on patients with liver diseases (24), post hoc subgroup analyses involving decreased detection power, increased alpha error, and loss of accurate randomization, and a lack of information related to the mechanisms by which glucoraphanin functions in the liver (25)
Consulting your practitioner before stopping is essential
Harling L, Rasoli S, Vecht JA, Ashrafian H, Kourliouros A, Athanasiou T
It is not recommended for individuals under the age of 18 or over the age of 75