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Nutrients 15(16):3523 Published 2023 Aug 10

First, melatonin appears most useful where oxidative load is high (e.g., PCOS, diminished ovarian reserve, repeat-poor response), aiming to improve oocyte/embryo competence rather than to replace first-line ovulation-induction strategies

For oral peptides, bioavailability is typically very low, often in the single digits, because the gastrointestinal tract destroys most of the compound before it can be absorbed

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