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The most cited mechanistic finding is from a 2017 study published in the Journal of Molecular Medicine , in which Hsieh and colleagues reported that BPC-157 promotes angiogenesis in CAM assay and tube formation assay and accelerated blood-flow recovery in a rat hindlimb ischemia model, with the effect attributed to activation of the VEGFR2AkteNOS signaling pathway [1]

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