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It has at times been granted a food-ingredient designation, which is not the same as approval to treat a medical condition

GS: synthesizes glutamine from ammonia NH3, and glutamate

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Because they increase insulin when needed and lower glucagon

Therefore, using a large, real-world population with type 2 diabetes, we constructed a model to assess the cost-effectiveness of widespread use of SGLT2is and GLP-1 RAs in people with type 2 diabetes, considering only major cardiovascular and kidney outcomes