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According to the 2023 Youth Risk Behavior Survey , only 3.4 percent of Massachusetts high school students reported currently smoking, defined as having used cigarettes at least once in the past 30 days, and just 0.9 percent reported daily use

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Cannabis use disorder Cannabis use disorder is characterized by symptoms such as intense cravings, an inability to stop/reduce use or continuing use despite negative consequences

The results showed that the expression levels of several chromatin-modifying enzymes, including histone acetyltransferase, histone methyltransferase, histone domain proteins, and histone kinase were significantly increased