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Fourth, given that the DIY methods may be potentially harmful due to chemical constituents of commercially available ingredients to make e-liquids 18,36 , we also categorized discussions related to the safety of ingredients and methods in our dataset

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In trials, people instructed to exclusively smoke very low nicotine cigarettes smoked fewer per day, showed less evidence of the kinds of physiological harms produced by cigarette smoking, and were more likely to try to quit after the trial was over