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Key points: A meta-analysis compared the impact of semaglutide and liraglutide on lowering blood sugar levels (measured by HbA1c) and suggested that semaglutide was more effective than liraglutide A randomised controlled trial conducted in 2022 investigated the impact of semaglutide and liraglutide on weight loss in individuals living with obesity The results showed that semaglutide was more effective at weight loss (15.8% body weight loss) than liraglutide (6.4% body weight loss) Semaglutide was also better tolerated than liraglutide, with fewer participants discontinuing treatment due to side effects, but GI-related issues were common in both groups Lifestyle interventions without semaglutide average around 5-10% weight loss, and less people achieve clinically significant weight loss without semaglutide 3) Whats the difference between Wegovy and Ozempic

Eur J Clin Pharmacol 74 , 147160 (2018)

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