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A limited number of clinical trials and case reports demonstrated that 1 h of compression with 193 mbar in the hyperbaric chamber, corresponding to a descent of 2250 m, lead to a short term improvement in symptoms of AMS but had no longterm beneficial effect

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The SUSTAIN-6 trial showed the effects of a once-weekly injection of semaglutide on cardiovascular events

The expected dosing schedule is: Weeks 14: 1.5mg once daily Weeks 58: 4mg once daily Weeks 912: 9mg once daily Week 13 onwards: 25mg once daily maintenance dose You may stay at a dose longer if your side effects dont settle down