In general, adverse side effects are observed with greater frequency at doses of sildenafil of 50 mg or greater, and particularly at doses of 75 mg or 100 mg or greater
The frequency of cognitive impairment in patients with anxiety, depression, and bipolar disorder: an unaccounted source of variance in clinical trials
[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Dai J., Liang K., Zhao S., Jia W., Liu Y., Wu H., Lv J., Cao C., Chen T., Zhuang S., et al
Side Effects: Starting with a low dose is recommended for all formulations of bupropion to minimize side effects like insomnia, restlessness, and agitation, which are common during the first few days of treatment
Context matters enormously here