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For class-level context, see DPP-4 Inhibitors and Weight Loss
This increased gut permeability can allow for high histamine foods to enter the bloodstream which otherwise would stay in the gut potentially leading to histamine intolerance
NPY/AgRP neurons play a role in appetite enhancement
Additionally, consuming foods high in antioxidants, such as fruits, vegetables, and nuts, can indirectly enhance glutathione levels
The mechanisms most cited in the literature are promotion of angiogenesis (new blood-vessel formation, linked to VEGFR2 signaling), modulation of growth-factor and nitric-oxide pathways, and interaction with the gut-brain axis
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