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303 Moreover, hepatic iron accumulation can induce the transcription expression of ACSL4 by activating the transcription factor c-Myc, and further aggravate the development of MASH through ferroptosis

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the cytosolic ones

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90 In this process, epithelial cells lose their characteristic structure and functions, including cell polarity, tight junctions, and intercellular adhesion, and gain the morphology and functions of mesenchymal cells, including cell migration, invasion, and resistance to apoptosis