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"Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1"

Systemically, it has shown promise in reducing inflammation-driven damage in neurodegenerative conditions, lung fibrosis, and even radiation-induced injuries, pointing to its broad-spectrum regenerative capacity

& Kass, R

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335,336 Further, the GLP-1/GIP dual-agonist tested in this study, MAR709, lost its superior efficacy on body weight and food intake over GLP-1 in the CNS-GIPR knockout mice, suggesting that this dual-agonist mediates part of its action via the CNS-GIPR