2.4 Detoxification action of glutathione S-transferases Glutathione S-transferases (glutathione sulfo-transferases, GSTs) are major phase II, GSH-dependent detoxication enzyme superfamily
Dingeo G, Brito A, Samouda H, Iddir M, La Frano MR, Bohn T
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Experimental Interaction and Research Focus Interaction with intracellular signalling networks in controlled laboratory models Influence on transcriptional behaviour and gene expression pathways Modulation of enzymatic sensitivity and biochemical response mechanisms Impact on mitochondrial activity and cellular energy regulation Support of repeat-exposure and comparative pathway validation studies Laboratory Research Applications Cellular Repair and Regeneration Research: Examining cellular response behaviour and regenerative pathway modelling in vitro
Eight slides from eight different rats per group were evaluated to assess and grade the varied pathological alterations observed in the studied brain tissues