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It has been shown to reduce osteoclast differentiation without affecting cell viability, and it can enhance osteoblast proliferation and differentiation by modulating the MEK signaling pathway in both osteoblasts and osteoclasts (137)

Shanahan CM (2007) Inflammation ushers in calcification: a cycle of damage and protection

Skin biopsy is also able to identify non-length-dependent neuropathies (e.g., ganglionopathies) through proximal versus distal biopsy comparisons [39]

Biology, Mendelian randomisation, and discordance data all point in that direction, but we are not there yet with trial data

The successful conjugation with the alkyne probes was further confirmed via fluorescent visualization on SDS-PAGE (Fig