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IEC6 cells were subjected to treatment with metformin alone, post-metformin treatment with the AMPK inhibitor (compound C), or rotenone, a known complex 1 inhibitor 42,43 , alone

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Addition of ZnONPs induced callus with greenish-brown friable callus at most concentrations, except at 16 mg L -1 , where the callus color was changed to green