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Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells

in vivo male flinders sensitive line (fsl) rats and male cd1 mice, exposed to model genetic and environmentally induced depression, respectively, were injected intraperitoneally with alcar 100 mg/kg for 21 days

As other Phase I studies using D+Q in the context of AD report out, we will be positioned to begin determining whether there is a convergence of data for specific disease states (e.g., NCT04785300 and NCT05422885 are both AD Phase I trials using D+Q), or study/site-specific changes are noted

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