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Likewise, these pharmacological activities attributed to Chrysanthellum americanum may be due to the presence of polyphenols, flavonoids and saponins in the aqueous extract, classified as large families of natural products, which have also demonstrated significant properties on the central nervous systems such as an affinity for GABA A complex receptors, inducing antiepileptogenesis and anticonvulsant effects [13] [39]

doi: 10.1210/endo-128-4-1857 70 JanvierSCheynsKCanfynMGoscinnySDe SpiegeleerBVanheeCet al

10.1038/ijo.2011.147 90 ShiraziR